This collection brings together publications drafted by members of the STAGE consortium.
They all relate to the project’s core research areas and are shared to help you explore, understand, and engage with our research.
Publication
Unified high-resolution immune cell fraction estimation in blood tissue from birth to old age
EMC – Guo X, Sulaiman M, Neumann A, Zheng SC, Cecil CAM, Teschendorff AE, Heijmans BT
Epigenetic research examines changes to the DNA that affect how active genes are. For this type of research, it is important to know from which cell type(s) the DNA come, because epigenetics are different between cells. As we often do not have exact information on the cell types, we use methods to estimate them. The cell types differ by age. Therefore, there are different methods for different age groups, but there is no one method available that can be used for all ages. In this project, we have developed such a method, called UniLIFE.
Bayesian Optimization over Bounded Domains with the Beta Product Kernel
Covariance functions for Bayesian optimization are typically defined over unbounded domains, while we define a natural bounded domain kernel that works better on optimizing model compression.
Requirements elicitation for a health monitoring mobile application: a participatory design approach with clinicians and researchers
The study looked at how to design a health app by working closely with doctors and researchers. A survey was used to find out what features the app should have. The results showed the app should be easy to use, track health automatically and manually, and include physical, mental, social, and environmental health. It also needs to follow strong ethical guidelines. People could use it for personal health, research, and making health decisions. In the future, patients and the public will help shape the app to make sure it’s useful and relevant for everyone.
Psychological stressors of imprisonment and coping of older incarcerated persons: a qualitative interview study
Study aimed to explore the key psychological stressors experienced by older imprisoned persons and their coping strategies. Qualitative interviews were conducted between April 2017 and December 2018 with a purposive sample of 79 participants from 2 different groups in Switzerland: older imprisoned persons (n = 50) and mental health professionals (n = 29) with experience working in prisons. This study has identified various ways in which the prison environment not only undermines older incarcerated persons´ psychological well-being, but also their ability to manage the stress they are experiencing.
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